Bill Mann discusses retail sales growing nearly 4% in January, Shopify's strong growth in 2021 being followed by slightly less growth in 2022, why shares of Shopify will never look cheap and the company's new partnership with JD.com. Also, Airbnb's record revenue last year, hotel stocks hitting new all-time highs, and the wisdom of Ron Gross. Finally, Olivia Zitkus and Keith Speights discuss a new wave of biosimilar drugs and the challenges (and opportunities for investors) they present.