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Adam Cox is joined by David Hallett from Exscientia. They discuss AI, in particular how it can help and streamline drug discovery. They also discuss which types of AI technology they're using at Exscientia. https://www.exscientia.com/

You might think that self care sounds somewhat selfish, but it's worth remembering that you can't pour from an empty cup. You need to look after yourself to be able to care for others. So if you're struggling with prioritising self care and to look out for your own interest, it's worth remembering those last two words of the instruction to love your neighbour — as yourself.

James Cameron-Wilson explains that box office is down 17%, with a big dropoff for the new Joker movie. He couldn't get excited by new #1 Transformers One. Being animated, it negates the wow factor and he was bored rigid. For the first time in his career, he thinks a film should not have gone on general release. #3 Terrifier 3 is a Christmas horror movie so strong some patrons have been made ill. James says it would have been banned in the 80s. Again he recommends people to catch Beetlejuice Beetlejuice or The Outrun, both still in the charts. On AppleTV+ he enjoyed Wolfs with George Clooney and Brad Pitt playing well off each other as rival fixers, even if it does get increasingly silly.

Steve Caplin delves into the world of tech. Tesla's Robotaxi disappointed investors. Standing desks turn out to be no better than being seated. A robotic finger can now be used for digital examinations. The Dresden Sinfoniker has a robot conductor – with three arms – to perform complex music. There's an electric version of the old BMW bubble car. You can buy Vespa scooters with 75mm anti-armour cannons attached. A bell has been designed for runners – at a price. And firemen at the Stadtallendorf fire station may be regretting not installing a fire alarm.

Political commentator Mike Indian looks ahead to the Budget, discussing whether Labour will be breaking its manifesto commitments, feeling that a time-limited wealth tax would be better than discouraging pension saving. He discusses the surprise ejection of James Cleverley from the Tory leadership contest, perhaps the one best placed to unify the party. He predicts that at the end of this Parliament, it will be Boris Johnson who is leader of the opposition. He also reflects upon the life of Alex Salmond, who so nearly became Prime Minister of an independent Scotland. He had flair and talent, though perhaps not integrity. The latter, in the long run, is more important in a politician.

Neil Shah of Edison Group finds London Tunnels' project fascinating. Despite the name, they are listed on Euronext and aim to turn the network of tunnels under Holborn Underground into a major tourist attraction. Although intended as air raid shelters they became a home for MI6 and ended up being used by the GPO. Details of a forthcoming presentation are on the Edison Group website. Card Factory is demonstrating that a combination of bricks and clicks could be more effective than a pure online operation. The company is expanding its product range, stores and its online business and is trading at a larger discount than it should be.

Five countries were recognised as nuclear weapon states under the 1970 Non-Proliferation Treaty: the United States, Russia, the United Kingdom, France and China. Other states now with nuclear weapons include India, Pakistan and North Korea — and Israel is thought to have them too. Alfred Nobel, who invented dynamite but was appalled at the thought that he would be remembered as leaving such a deadly legacy, would be pleased with the Nobel Committee's decision to issue such a clear warning against any future use of nuclear weapons. Background music: 'Sarabande' by Joel Cummins Image source: Wikipedia

Savings plans to help financial resilience — are they any use? New tipping rules, and parents helping as mortgage lenders. Georgie Frost, Simon Lambert and Lee Boyce discuss (Lee also shares thoughts about his various collections over the years).

Investors get their first glimpse at Tesla’s robotaxi ambitions and how regulators might be looking to break up search giant Google. Jason Moser and Andy Cross discuss why Jamie Dimon is trying to get investors past the rate story in banking, Tesla’s splashy We, Robot product event, and how the company’s new Cybercab offering might fit into the company’s long-term strategy, and earnings updates from Delta, Pepsi, and Domino’s. Then, 19 minutes in, the DOJ’s taking a much closer look at Alphabet’s Google and its online search empire. Andy and Jason talk through what a Google break-up would mean, and why it’s a bit weird to be talking about Google the monopoly as its power seems to be waning. Finally, 32 minutes in, Jason and Andy field a question from a listener on following earnings and offer up two stocks on their radar: Netflix and Meta. Stocks discussed: JPM, WFC, TSLA, DAL, PEP, DPZ, NFLX, META. Host - Dylan Lewis; Guests - Jason Moser, Andy Cross

Analysts at Jeffries estimate that Hurricane Milton will have done $50-to-$175 billion in damage. Matt Frankel and Ricky Mulvey discuss how insurers prepare for catastrophic losses, what extreme weather events mean for homeowners, car owners, and the commercial real estate market, and why Alex Chriss gets an A for his first year leading PayPal. Then, 14 minutes in, Robert Brokamp joins Alison Southwick to answer listener questions about saving for college, finding a financial advisor, and estate planning. Companies discussed: BRK.A, BRK.B, SPG, UVE, PYPL. Host- Ricky Mulvey; Guests - Matt Frankel, Alison Southwick, Robert Brokamp